Element AVITI24™ System

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PRODUCTS

Instrument & Platform

Rapid and precise multi-omics analysis and NGS platform.

High-Performance Technology

Analyze RNA, protein, and morphology in 1 sample

Rapid Capability

Profile up to 2M cells in 24hrs on dual flow cells

High-Sensitivity Characteristic

Capture transcripts and proteins with sensitivity and specificity

Quick Efficiency

Prepare cell samples in 45 minutes hands-on time

Content Introduction File Download

Content Introduction

Introduction

AVITI24™ Introduction

The AVITI24™ System with Teton™ CytoProfiling simultaneously measures a diverse array of molecular features in up to 1 million cells per flow cell for deep multi-omic profiling of adherent cells or cell suspensions.

From a single sample, you can analyze RNA, proteins, and cell morphology in 24 hours. On the same system, the AVITI24™ delivers high-quality next‑generation sequencing (NGS) data with uncompromising performance, flexibility, affordability, and access to a range of assays from whole-genome sequencing to targeted panels.

Analyze RNA, protein, and morphology in a single sample
Profile up to 2 M cells in 24 hours on dual flow cells
Capture transcripts and proteins with sensitivity and specificity
Prepare cell samples in 45 minutes of hands-on time

Powered by ABC sequencing

Avidite-based chemistry (ABC) harnesses the power of ultra‑stable avidites to deliver high-quality data quickly and more cost-effectively than ever. Our 100-fold reagent dilution translates directly to per-run savings for your lab.

AVITI generates polonies with rolling circle amplification (RCA).

Each polony is a continuous DNA strand with many sequencing sites.

RCA eliminates PCR error propagation and index hopping while reducing AT/GC bias.

An avidite is a dye-labeled polymer decorated with multiple copies of the same nucleotide.

One avidite binds to a polony at multiple sites, creating a very stable binding complex.

Stable binding allows 100-fold lower reagent concentrations, reducing costs while improving accuracy.

Additional ABC advantages

ABC supports unique molecular identifiers (UMI), single- or dual-indexing, and single-read or paired-end runs to qualify a breadth of NGS capabilities on a single instrument:

Short-insert sequencing
Long-insert sequencing
Synthetic long reads
DNA sequencing
RNA sequencing (RNA-Seq), including single cell

About Element Biosciences

Element Biosciences is a pioneering life science company developing innovative technologies that empower the scientific community with more freedom and flexibility to accelerate their scientific discoveries. By reinventing every fundamental element of the assay system, we’ve created disruptive DNA sequencing and multiomics tools, including our family of AVITI™ systems. The AVITI benchtop instrument uses proprietary technology to deliver high-quality sequencing at low run costs, accessible for any scale of research operation. Leveraging our revolutionary technology, we are adding to these capabilities, improving standard workflows, and providing multiomic readouts.

Single-cell/RNA Sequencing

Validated compatibility with leading single-cell solutions delivers an end-to-end solution predicated on cost-efficiency and sensitivity.

Low-Pass Sequencing

High effective coverage joins established analysis solutions to ensure an end-to-end sequencing solution that is affordable on a per-sample basis.

Exomes and Targeted Sequencing

Batching of 8–24 exomes per flow cell or 16–48 exomes per run enables in-house tumor-normal studies without the wait to fill a flow cell.

Whole-Genome Sequencing

Industry-leading accuracy improves variant detection and yields a greater proportion of usable data.

More Applications

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Asia Pathogenomics (APG)